Eczema and Menopause: Why Your Skin Is Flaring and How to Fix It

How to Manage Atopic Dermatitis During Menopause

How to Manage Atopic Dermatitis During Menopause
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Menopause comes with a lot of symptoms — hot flashes and night sweats among the more well-known. But there are many other ways the hormonal changes of menopause affect your body, including your skin.

Skin sensitivity and itching can be a silent symptom of menopause. In addition, many women in the menopausal transition experience new atopic dermatitis (eczema) or a worsening of existing flares and symptoms.

 That’s why managing atopic dermatitis in your forties and fifties requires shifting the way you care for your skin. Here’s how you can take care of sensitive, irritated, itchy, dry skin during this time.

How Estrogen Loss Weakens the Skin Barrier

During perimenopause, estrogen levels begin to decline.

 “When estrogen declines, the skin’s ‘protective seal’ becomes less efficient,” explains Natalie Matthews, MD, a board certified dermatologist at Henry Ford Health in Detroit. “Moisture escapes more easily, and irritants enter more easily, which is the environment where eczema can flare,” she explains. In addition, estrogen supports skin’s structural components, collagen and elastin, and its loss contributes to skin thinning.

With this breakdown in the skin barrier, you may have skin inflammation, irritation, and itch, says Dr. Matthews. Among women in perimenopause and menopause, eczema was the most commonly reported skin problem, according to one large observational study.

Adapting Your Skin-Care Routine

There are a couple things that your skin may need during this time: more moisturizing products and possibly a change in products you’re using. “A common complaint I hear from patients is that they’ve been using a particular product for 20 years and their skin is reacting to it, but [they think] they can’t possibly have a problem with it now. I explain that their body has developed a sensitivity to it,” says Aleksandra Brown, DO, board certified dermatologist at River Ridge Dermatology in Blacksburg, Virginia. If that sounds like you, here’s how to start making skin-healthy changes.

Step 1: Change Your Cleanser (Maybe)

If you use a foaming cleanser, switch to more hydrating cream or oil-based body and face washes, says Dr. Brown. In addition, avoid products, including laundry detergent, that contain fragrance, a common irritant. Look for those labeled “fragrance-free” and rinse with lukewarm, not hot, water, Matthews adds.

Step 2: Barrier Protection

Apply thick moisturizers to damp skin twice a day, recommends Brown. For example, moisturize within a few minutes of getting out of the shower, she says. That may mean upgrading from a lotion to a cream or ointment, as well as choosing products that contain hydrating, barrier-repair ingredients like ceramides, fatty acids, and cholesterol, recommends Monique Chheda, MD, a board certified dermatologist in McLean, Virginia.

Step 3: Examine Your Actives

If you’re using a retinoid or retinol, which speeds up skin cell turnover and encourages collagen production,

 but you find that your skin can’t tolerate it now, there are ways to shift your approach with these anti-aging active ingredients. For her perimenopause patients, Brown might recommend using retinoids less often, such as every other night instead of nightly.

Similarly, if you’ve been using glycolic acid for exfoliation, you might switch to a more gentle lactic acid or use it every other week, Brown says. “We want to exfoliate, but we need to be gentle about it,” she says. Finally, remember that less is more. Using multiple products that encourage skin cell turnover can cause more flares of irritation and redness.

Medical Interventions: Topicals and Beyond

Matthews recommends seeing a dermatologist in these instances:

  • Your skin continues to flare, worsen, or not improve despite the gentle skin-care tips above.
  • Your skin is painful, cracked, or infected.
  • Your eczema rash is persistent, worsening, or widespread.
Your dermatologist can treat atopic dermatitis with prescription-strength topicals, such as a short, two-week course of steroid cream to quiet a flare, says Brown. Other prescription treatments including topical and oral JAK inhibitors and injectable biologics like dupilumab (Dupixent) may be necessary for moderate to severe atopic dermatitis.

The Role of Menopausal Hormone Therapy

Given that estrogen decline is affecting your skin, can menopausal hormone therapy (MHT) help restore skin to its youthful condition? “Several studies have shown that systemic estrogen therapy can increase dermal collagen content, improve skin thickness, and enhance hydration in postmenopausal women,” says Dr. Chheda.

But says Chheda, MHT is indicated for treating menopausal symptoms like hot flashes and night sweats. “Hormone therapy is not prescribed solely for skin changes or symptoms. Any skin benefit is considered secondary,” she says. Speak to a menopause-educated clinician about MHT if you’re interested in this treatment.

Lifestyle Tweaks for the Menopausal Flare

If your skin is rashy and itchy, there are various adjustments you can make to your clothing, temperature, and stress.

  • Let your clothes give your skin TLC. Wear soft, breathable fabrics, and avoid rough materials, says Matthews.
  • Keep the air moist. If the air in your home is dry, consider a humidifier, says Chheda.
  • Don’t leave sweat on your skin. Sweat may trigger flares, so rinse off after sweating, says Chheda.
  • Manage stress. Stress does not cause eczema, but it can worsen flares,” says Matthews. While some stress is inevitable, finding management strategies (like yoga, quiet reading, running, or a weekly painting class) can help your mental state.
  • Eat a balanced diet. “An overall anti-inflammatory eating pattern rich in fruits, vegetables, fiber, and omega-3 fatty acids may help support skin barrier function and immune balance,” says Chheda.

The Takeaway

  • Skin undergoes significant changes during the menopausal transition.
  • A decline in the hormone estrogen leads to a loss of collagen and elastin, as well as a weakened skin barrier that leads to inflammation, irritation, and itch.
  • You can reduce irritation by using thicker moisturizers with ingredients like ceramides, changing how you use active ingredients like retinoids, avoiding fragrances in skin-care and laundry products, and making lifestyle changes like wearing soft, breathable clothing.
  • If skin does not improve, see a dermatologist who can evaluate you and possibly prescribe topical, oral, or injectable medications that treat atopic dermatitis.

Resources We Trust

EDITORIAL SOURCES
Everyday Health follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, board-certified medical experts, patients with lived experience, and information from top institutions.
Resources
  1. Kamp E et al. Menopause, Skin and Common Dermatoses. Part 2: Skin Disorders. Clinical and Experimental Dermatology. October 26, 2022.
  2. Perimenopause. Cleveland Clinic. August 8, 2024.
  3. Viscomi B et al. Managing Menopausal Skin Changes: A Narrative Review of Skin Quality Changes, Their Aesthetic Impact, and the Actual Role of Hormone Replacement Therapy in Improvement. Journal of Cosmetic Dermatology. August 23, 2025.
  4. Retinoid or Retinol? American Academy of Dermatology Association. May 25, 2021.
  5. Gallagher K et al. New treatments in atopic dermatitis update. Annals of Allergy, Asthma & Immunology. November 2025.
Susan-Bard-bio

Susan Bard, MD

Medical Reviewer

Susan Bard, MD, is a clinical instructor in the department of dermatology at Weill Cornell Medicine and an adjunct clinical instructor in the department of dermatology at Mount Sinai in New York City. Her professional interests include Mohs micrographic surgery, cosmetic and laser procedures, and immunodermatology.

She is a procedural dermatologist with the American Board of Dermatology and a fellow of the American College of Mohs Surgery.

Dr. Bard has written numerous book chapters and articles for many prominent peer-reviewed journals, and authored the textbook The Laser Treatment of Vascular Lesions.

Jessica Migala

Author

Jessica Migala is a freelance writer with over 15 years of experience, specializing in health, nutrition, fitness, and beauty. She has written extensively about vision care, diabetes, dermatology, gastrointestinal health, cardiovascular health, cancer, pregnancy, and gynecology. She was previously an assistant editor at Prevention where she wrote monthly science-based beauty news items and feature stories.

She has contributed to more than 40 print and digital publications, including Cosmopolitan, O:The Oprah Magazine, Real Simple, Woman’s Day, Women’s Health, Fitness, Family Circle, Health, Prevention, Self, VICE, and more. Migala lives in the Chicago suburbs with her husband, two young boys, rescue beagle, and 15 fish. When not reporting, she likes running, bike rides, and a glass of wine (in moderation, of course).