Can Wet Wrap Therapy Help Severe Eczema (Atopic Dermatitis) Flares?

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Is It Time to Change Your Severe Eczema Treatment?
Wet Wrap Therapy Basics
Melissa Piliang, MD, a dermatologist at Cleveland Clinic in Ohio, recommends wet wraps for people with moderate to severe eczema who are experiencing extreme itchiness or pain. “The warm, wet wraps can be very soothing to the irritated, inflamed skin,” she says, adding that the therapy is especially helpful for flares that are widespread, such as those covering a large area on an arm or leg.
Wet Wrap Therapy Can Be an Eczema Treatment Option for Children
“The typical candidate for wet wrap therapy is a young child with a severe eczema flare, especially if they’ve already been using topical steroids or topical calcineurin inhibitors,” says Breanne Mordorski, MD, a dermatologist at Northwell Health in New York City.
“For these patients, wet wraps are a good second-line option when traditional topical treatments fail [on their own],” Dr. Mordorski says.
She says that wet wraps can also be helpful for children during a severe eczema flare-up when there are delays in accessing systemic medications, such as a biologic.
Wet Wrap Therapy for Babies Can Be Helpful, if Done With Care
Dr. Montejo says that wet wrap therapy should be used for babies and other young children only under the direction of a medical provider.
Wet Wrap Therapy Might Be Harder for Some Adults and Older Children
Adults and older children with larger bodies — and more surface area — may not fare as well with wrap treatment, Mordorski says, especially when it’s applied at home or in a doctor’s office. But they may do well in the hospital when admitted for a severe flare.
For older people with severe atopic dermatitis, Mordorski says wet wraps can be used as a stopgap to manage a severe flare-up during the wait for longer-term systemic eczema therapy to take effect.
Pros and Cons of Wet Wrap Therapy
Wet wraps can also trap moisture, causing inflamed hair follicles, which can lead to blistered skin and infection. In rare cases, and especially when wet wraps are used too long or incorrectly, there is a risk of serious infection, Mordorski says.
Some Doctors Aren’t Fans of Wet Wrap Therapy
Not all dermatologists recommend wet wraps. A. Yasmine Kirkorian, MD, the chief of dermatology at Children’s National Hospital and an associate professor of dermatology at the George Washington University School of Medicine and Health Sciences in Washington, DC, believes there are better alternatives.
Kirkorian says the availability of FDA-approved systemic medications for the treatment of refractory (treatment-resistant) atopic dermatitis in children may override the need for wet wrap therapy in these cases.
“Any child with severe atopic dermatitis — extensive body surface area involved, not responding to first-line treatments, waking up nightly from itching, sustaining skin infections, missing school for eczema, going to the ER or being hospitalized for eczema — should be evaluated by a board-certified dermatologist or pediatric dermatologist,” Kirkorian says.
If you’re on TikTok or Instagram, Sheilagh Maguiness, MD, a pediatric dermatologist and professor of dermatology at the University of Minnesota Medical School in Minneapolis, offers lots of advice on products for wet wrap therapy, as well as techniques.
Your doctor will tell you if wet wrap therapy is right for you or your child, how and when to do it, and how to look for signs of skin infection.
The Takeaway
- Wet wrap therapy is a short-term therapy, typically used for severe atopic dermatitis (eczema) flares in children and adults, to lessen itching and pain, and allow skin to heal.
- It involves applying topical medication and moisturizer after bathing, followed by wet cotton clothing or bandages, then a dry layer of clothing.
- While it can be an effective way to treat eczema, it may not be well tolerated; it can also increase the absorption and potency of topical medications like steroids, and it may increase the risk of certain infections.
- Wet Wrap Therapy. National Eczema Association. March 14, 2025.
- Nelson S. The Complex Science Behind Itch in Atopic Dermatitis. National Eczema Association. July 30, 2021.
- Atopic Dermatitis (Eczema): Diagnosis & Treatment. Mayo Clinic. May 15, 2024.
- Chaudhary F et al. Exploring the Complexities of Atopic Dermatitis: Pathophysiological Mechanisms and Therapeutic Approaches. Journal of Biotechnology and Biomedicine. July 17, 2024.
- Ludmann P. Eczema Types: Atopic Dermatitis Symptoms. American Academy of Dermatology Association. October 10, 2023.
- Atopic Dermatitis: Treatment and Prevention. University of Central Florida Health.
- Stein S et al. How to Treat & Control Eczema (Atopic Dermatitis) Rashes in Children. American Academy of Pediatrics. May 14, 2025.
- Eczema in Children. National Eczema Association.
- Eczema - Using Wet Wraps. Children’s Health Queensland. October 2023.
- Calabrese G et al. Topical and Conventional Systemic Treatments in Atopic Dermatitis: Have They Gone Out of Fashion? Dermatology Practical & Conceptual. January 2022.
- Eczema. Cleveland Clinic. October 25, 2022.
- Understanding Weeping Eczema: Causes, Symptoms and Treatment Options. Indiana University School of Medicine. October 22, 2024.
- Topical Steroids and Risk. National Eczema Association.

Jon E. Stahlman, MD
Medical Reviewer
Jon E. Stahlman, MD, has been a practicing allergist for more than 25 years. He is currently the section chief of allergy and immunology at Children’s Healthcare of Atlanta's Scottish Rite campus and the senior physician at The Allergy & Asthma Center in Atlanta. He served as the president of the Georgia Allergy Society, has been named a Castle Connolly Top Doctor, and was listed as a Top Doctor by Atlanta magazine. His research interests include new therapies for asthma and allergic rhinitis as well as the use of computerized monitoring of lung function.
He received his bachelor's and medical degrees from Emory University. He completed his pediatric residency at Boston Children’s Hospital and his fellowship in allergy and clinical immunology at Harvard University’s Boston Children’s Hospital and Brigham and Women’s Hospital. After his training, Dr. Stahlman conducted two years of clinical research at Boston Children’s Hospital and was part of the faculty at Harvard Medical School, where he taught medical students and allergy and immunology fellows.
Stahlman is board-certified and recertified in allergy and clinical immunology. He served as a principal investigator on phase 2 through 4 studies that are responsible for most of the U.S. Food and Drug Administration–approved therapies for allergies and asthma available today.
Outside of the office, he centers his interests around his wife and three daughters, coaching soccer for many years, and his hobbies include cycling and triathlons.

Amy Sacks, MPH
Author
Amy Sacks, MPH, is a freelance health and medical writer interested in everything from food and nutrition to infectious diseases and animal welfare. She is seasoned former news reporter with over 20 years of experience in print, online, and social media journalism. She began her career as a general assignment reporter for the New York Daily News, where she also wrote the weekly Critters column. Her work has appeared in Newsday, DNAinfo.com, The Advocate, MAMM, and other publications.
She spent the last decade writing about a wide range of health topics for academic medicine and wrote extensively about COVID-19 during the pandemic, earning a silver GIA award from the Association of American Medical Colleges. She currently serves as a medical and science writer and directs internal communications for the departments of pathology and medicine at the Albert Einstein College of Medicine and Montefiore Health System in the Bronx, NYC.
She received a master’s degree from the Columbia University Graduate School of Journalism and a master’s in public health from the CUNY School of Public Health at Hunter College. Prior to journalism school, she spent three years in Japan writing about art and travel. Sacks lives in Manhattan with her partner, George, and their dog, Bohdi, and is deeply passionate about local NYC issues and policies. In her free time, she can be found walking from one end of the city to the other and preparing healthy meals at Gods Love We Deliver.