Zenocutuzumab (Intravenous)
Zenocutuzumab is used in adults to treat certain types of lung and pancreatic cancer that cannot be removed with surgery or has spread to other parts of the body (metastatic).
Zenocutuzumab is given after other treatments did not work or stopped working.
Your doctor will make sure you have the correct tumor type to be treated with zenocutuzumab.
Zenocutuzumab may also be used for purposes not listed in this medication guide.
warnings
What is the most important information I should know about Zenocutuzumab (Intravenous)?
Tell your doctor if you have or have ever had:
- lung or breathing problems (other than lung cancer); or
- heart problems such as congestive heart failure.
May harm an unborn baby. Do not use if you are pregnant. You may need to have a negative pregnancy test before starting this treatment. Use effective birth control while using zenocutuzumab and for at least 2 months after your last dose. Tell your doctor if you become pregnant.
Do not breastfeed while using this medicine, and for at least 2 months after your last dose.
Side Effects
What are the side effects of Zenocutuzumab (Intravenous)?
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Some serious side effects may occur during the injection. Tell your medical caregiver if you feel dizzy, nauseated, light-headed, itchy, sweaty, or have a headache, chest tightness, back pain, trouble breathing, or swelling in your face.
Call your doctor at once if you have:
- feeling light-headed, loss of consciousness;
- new or worsening breathing problems--trouble breathing, shortness of breath, cough, fever; or
- new or worsening heart problems--swelling, rapid weight gain, feeling short of breath, cough, tiredness, irregular heartbeats.
Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.
Common side effects may include:
- nausea, vomiting, diarrhea, constipation, stomach pain;
- swelling in your breast, face, ankles or legs;
- tiredness, muscle or bone pain;
- skin rash;
- abnormal liver function tests;
- low red blood cell and platelet counts;
- low sodium, magnesium, and phosphate levels; or
- abnormal blood clotting tests.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I take Zenocutuzumab (Intravenous) if I’m pregnant or breastfeeding?
May harm an unborn baby. Do not use if you are pregnant. You may need to have a negative pregnancy test before starting this treatment. Use effective birth control while using zenocutuzumab and for at least 2 months after your last dose. Tell your doctor if you become pregnant.
Do not breastfeed while using this medicine, and for at least 2 months after your last dose.
Interactions
What drugs and food should I avoid while taking Zenocutuzumab (Intravenous)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Dosage Guidelines & Tips
How to take Zenocutuzumab (Intravenous)?
Use Zenocutuzumab (Intravenous) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Your doctor will perform tests to make sure zenocutuzumab is the right treatment for you.
Zenocutuzumab is given as an infusion into a vein. A healthcare provider will give you this injection.
Zenocutuzumab is usually given once every 2 weeks. Your doctor will determine how long to treat you with this medicine.
You will be watched during and after your infusion to make sure you do not have an allergic reaction or serious side effects.
You may need frequent medical tests and your cancer treatments may be delayed based on the results.
You may need medical tests to check your heart function before and during treatment with zenocutuzumab.
You may be given other medications to help prevent serious side effects or allergic reaction. Keep taking these medicines for as long as your doctor has prescribed.
Call your doctor for instructions if you miss an appointment for your zenocutuzumab injection.
Overdose Signs
What happens if I overdose on Zenocutuzumab (Intravenous)?
In a medical setting an overdose would be treated quickly.