Wayrilz (Oral)
Rilzabrutinib is used in adults to treat recurring or chronic immune thrombocytopenia (ITP).
Rilzabrutinib is given after other treatments did not work or stopped working.
Rilzabrutinib may also be used for purposes not listed in this medication guide.
uses
What is Wayrilz (Oral) used for?
- Thrombocytopenia Autoimmune
warnings
What is the most important information I should know about Wayrilz (Oral)?
Tell your doctor if you have or have ever had:
- liver or kidney disease.
May harm an unborn baby. You may need a pregnancy test to make sure you are not pregnant. Use effective birth control while using rilzabrutinib and for at least 1 week after your last dose. Tell your doctor if you become pregnant.
Do not breastfeed while using this medicine, and for at least 1 week after your last dose.
Side Effects
What are the side effects of Wayrilz (Oral)?
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- liver problems--loss of appetite, nausea, vomiting, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
- signs of infection--fever, chills, sore throat, body aches, unusual tiredness, loss of appetite, bruising or bleeding.
Common side effects may include:
- headache;
- diarrhea, stomach pain, nausea; or
- COVID-19 infection.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I take Wayrilz (Oral) if I’m pregnant or breastfeeding?
May harm an unborn baby. You may need a pregnancy test to make sure you are not pregnant. Use effective birth control while using rilzabrutinib and for at least 1 week after your last dose. Tell your doctor if you become pregnant.
Do not breastfeed while using this medicine, and for at least 1 week after your last dose.
Interactions
What drugs and food should I avoid while taking Wayrilz (Oral)?
Grapefruit, Seville oranges, and starfruit may interact with rilzabrutinib and cause side effects. Avoid consuming grapefruit and starfruit products and orange marmalades.
Ask your doctor before taking an antacid, and take only the type your doctor recommends.
Dosage Guidelines & Tips
How to take Wayrilz (Oral)?
Use Wayrilz (Oral) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Rilzabrutinib is usually taken twice per day. Follow your doctor's instructions.
Take with a full glass of water.
You may take rilzabrutinib with or without food, but take it the same way each time.
Take with food if rilzabrutinib upsets your stomach or you experience diarrhea or nausea.
Swallow the tablet whole and do not crush, chew, or break it.
Do not stop taking this medicine without your doctor's advice.
You will need frequent blood tests to check your liver function, before you start and during treatment.
You may get infections more easily, even serious or fatal infections. You will need frequent medical tests and your doctor will check you for signs of infection during your treatment with rilzabrutinib.
Store this medicine in the original package at room temperature away from moisture, heat, and light.
Take the missed dose as soon as you can on the same day, and keep at least 2 hours between doses. Do not take two doses at one time.
Overdose Signs
What happens if I overdose on Wayrilz (Oral)?
Images
P, 400
Color: orange
Shape: capsule
Form: film coated
Imprint: P, 400