Voranigo (Oral)
Vorasidenib is used to treat certain types of brain tumors following surgery in adults and children at least 12 years old.
Your doctor will make sure you have the correct gene mutation to be treated with vorasidenib.
Vorasidenib may also be used for purposes not listed in this medication guide.
warnings
What is the most important information I should know about Voranigo (Oral)?
Tell your doctor if you have or have ever had:
- if you smoke cigarettes (tobacco);
- liver disease; or
- kidney disease (or if you are on dialysis).
Vorasidenib can harm an unborn baby if the mother or the father is using this medicine.
- If you are a woman, you may need a pregnancy test to make sure you are not pregnant. Use a barrier birth control method while using this medicine and for at least 3 months after your last dose.
- If you are a man, use birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last dose.
- Tell your doctor right away if a pregnancy occurs or think a pregnancy has occurred.
Vorasidenib can make hormonal birth control less effective, including birth control pills, injections, implants, skin patches, and vaginal rings. Use barrier birth control to prevent pregnancy: condom, diaphragm, cervical cap, or contraceptive sponge.
Vorasidenib may affect fertility in men or women. Pregnancy could be harder to achieve while either parent is using this medicine.
Do not breastfeed while using this medicine, and for at least 2 months after your last dose.
Side Effects
What are the side effects of Voranigo (Oral)?
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- liver problems--loss of appetite, nausea, vomiting, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Your cancer treatments may be reduced, delayed, or permanently discontinued if you have certain side effects.
Common side effects may include:
- headache, nausea, diarrhea;
- seizures;
- abnormal liver function tests;
- feeling weak or tired;
- COVID-19 infection; or
- muscle stiffness or aches.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I take Voranigo (Oral) if I’m pregnant or breastfeeding?
Vorasidenib can make hormonal birth control less effective, including birth control pills, injections, implants, skin patches, and vaginal rings. Use barrier birth control to prevent pregnancy: condom, diaphragm, cervical cap, or contraceptive sponge.
Do not breastfeed while using this medicine, and for at least 2 months after your last dose.
Interactions
What drugs and food should I avoid while taking Voranigo (Oral)?
Avoid smoking, since it can make vorasidenib less effective.
Dosage Guidelines & Tips
How to take Voranigo (Oral)?
Use Voranigo (Oral) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Swallow the tablet whole with a full glass of water and do not crush, chew, or break it.
Take with or without food, at the same time each day. Follow your doctor's instructions.
Doses are based on weight in children and teenagers. Your child's dose may change if the child gains or loses weight.
Do not change your dose or stop using vorasidenib without your doctor's advice.
If you vomit shortly after taking vorasidenib, do not take another dose. Take your next dose as scheduled.
Your blood may need to be tested often, including tests to check your liver function. Your cancer treatments may be reduced, delayed, or discontinued based on the results.
Store at room temperature away from moisture and heat. Keep the tablets in their original container, along with the packet or canister of moisture-absorbing preservative.
Use the medicine as soon as you can, but skip the missed dose if you are more than 6 hours late for the dose. Do not use two doses at one time.
Overdose Signs
What happens if I overdose on Voranigo (Oral)?
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