Tryngolza Autoinjector (Subcutaneous)
Olezarsen is used together with a low-fat diet to reduce triglycerides (a type of fat in the blood) in adults with familial chylomicronemia syndrome (a condition that prevents the body from breaking down fats).
Olezarsen may also be used for purposes not listed in this medication guide.
uses
What is Tryngolza Autoinjector (Subcutaneous) used for?
- Chylomicronemia Syndrome
warnings
What is the most important information I should know about Tryngolza Autoinjector (Subcutaneous)?
You should not use olezarsen if you are allergic to it.
It is not known if olezarsen will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Ask a doctor if it is safe to breastfeed while using this medicine.
Side Effects
What are the side effects of Tryngolza Autoinjector (Subcutaneous)?
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Stop using olezarsen and call your doctor at once if you have:
- bronchospasm (wheezing, chest tightness, trouble breathing);
- chills, muscle pain;
- severe itching; or
- skin redness or a rash that spreads.
Common side effects may include:
- pain, redness, bruising, swelling, or irritation where the medicine was injected;
- low levels of platelets in your blood; or
- joint pain or stiffness.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I take Tryngolza Autoinjector (Subcutaneous) if I’m pregnant or breastfeeding?
It is not known if olezarsen will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Ask a doctor if it is safe to breastfeed while using this medicine.
Interactions
What drugs and food should I avoid while taking Tryngolza Autoinjector (Subcutaneous)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Dosage Guidelines & Tips
How to take Tryngolza Autoinjector (Subcutaneous)?
Use Tryngolza Autoinjector (Subcutaneous) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Olezarsen is injected under the skin, usually once a month. A healthcare provider will show you where to inject olezarsen.
Ask your doctor or pharmacist if you don't understand how to use an injection.
Prepare an injection only when you are ready to give it. Call your pharmacist if the medicine looks cloudy, has changed colors or has particles in it.
Throw away the autoinjector after one use, even if there is still medicine left inside.
Your treatment may also include diet, exercise, weight control, and blood tests. Follow your doctor's instructions very closely.
Store this medicine in the original container in the refrigerator. Protect from light and do not freeze or shake the medicine.
Take the medicine out of the refrigerator and let it reach room temperature before using.
Do not warm the medicine with hot water, sunlight, or a microwave.
You may store this medicine at room temperature for up to 6 weeks. Throw the medicine away if not used within 6 weeks. Do not put it back into the refrigerator. Protect from heat.
Use the medicine as soon as you remember, and then go back to your regular schedule. Do not use two doses at one time.