Sugammadex (Bridion)
Sugammadex is used in adults and children during surgery to reverse the effects of certain muscle-relaxing medicines, such as rocuronium and vecuronium.
Sugammadex helps restore muscle function that was blocked during surgery.
Sugammadex may also be used for purposes not listed in this medication guide.
uses
What is Sugammadex (Bridion) used for?
- Reversal of Nondepolarizing Muscle Relaxants
warnings
What is the most important information I should know about Sugammadex (Bridion)?
You should not be treated with sugammadex if you are allergic to it.
Tell your doctor if you have or have ever had:
- a bleeding or blood clotting disorder such as hemophilia;
- low levels of platelets in your blood;
- a breathing disorder;
- liver disease; or
- kidney disease (or if you are on dialysis).
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.
Sugammadex can make hormonal birth control less effective. For at least 7 days after you receive sugammadex, use a non-hormonal back-up birth control (condom or diaphragm with spermicide) to prevent pregnancy. Hormonal contraception (birth control pills, injections, implants, skin patches, and vaginal rings) may not be effective enough to prevent pregnancy during this time.
It is not known whether sugammadex passes into breast milk. Tell your doctor if you are breastfeeding.
Side Effects
What are the side effects of Sugammadex (Bridion)?
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Tell your medical caregivers right away if you have:
- flushing (sudden warmth, redness, or tingly feeling);
- itching;
- wheezing, trouble breathing;
- weak or shallow breathing; or
- slow heartbeats.
Common side effects may include:
- nausea, vomiting;
- pain;
- headache; or
- low blood pressure.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I take Sugammadex (Bridion) if I’m pregnant or breastfeeding?
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.
Sugammadex can make hormonal birth control less effective. For at least 7 days after you receive sugammadex, use a non-hormonal back-up birth control (condom or diaphragm with spermicide) to prevent pregnancy. Hormonal contraception (birth control pills, injections, implants, skin patches, and vaginal rings) may not be effective enough to prevent pregnancy during this time.
It is not known whether sugammadex passes into breast milk. Tell your doctor if you are breastfeeding.
Interactions
What drugs and food should I avoid while taking Sugammadex (Bridion)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Dosage Guidelines & Tips
How to take Sugammadex (Bridion)?
Use Sugammadex (Bridion) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Sugammadex is injected into a vein through an IV. A healthcare provider will give you this medicine in a single injection.
Your breathing, blood pressure, oxygen levels, heart rate, and other vital signs will be watched closely while you are receiving sugammadex.
Sugammadex is used as a single dose and does not have a daily dosing schedule.
Overdose Signs
What happens if I overdose on Sugammadex (Bridion)?
In a medical setting an overdose would be treated quickly.