Rimabotulinumtoxinb (Myobloc)(Intramuscular)
RimabotulinumtoxinB, also called botulinum toxin type B, is made from the bacteria that causes botulism. Botulinum toxin blocks nerve activity in the muscles, causing a temporary reduction in muscle activity.
RimabotulinumtoxinB is used in adults to treat abnormal head position and neck pain due from cervical dystonia.
RimabotulinumtoxinB is also used in adults to treat chronic drooling (sialorrhea).
RimabotulinumtoxinB may also be used for purposes not listed in this medication guide.
uses
What is Rimabotulinumtoxinb (Myobloc)(Intramuscular) used for?
- Cervical Dystonia
- Sialorrhea
warnings
What is the most important information I should know about Rimabotulinumtoxinb (Myobloc)(Intramuscular)?
You should not be treated with rimabotulinumtoxinB if you are allergic to it or to any other botulinum toxin injection, such as onabotulinumtoxinA, abobotulinumtoxinA, or incobotulinumtoxinA, or if you have an infection in the area where the medicine will be injected.
Tell your doctor if you have ever had a side effect after receiving a botulinum toxin.
Tell your doctor if you have or have ever had:
- a nerve-muscle disorder, such as myasthenia gravis, ALS (Lou Gehrig's disease), or Lambert-Eaton syndrome;
- a breathing disorder or problems such as asthma or emphysema;
- droopy eyelids;
- problems with swallowing;
- bleeding problems;
- surgery on your face;
- a planned surgery; or
- received other botulinum toxin injection in the past 4 months.
RimabotulinumtoxinB is made from donated human plasma and may contain viruses or other infectious agents. Donated plasma is tested and treated to reduce the risk of contamination, but there is still a small possibility it could transmit disease. Ask your doctor about any possible risk.
It is not known if rimabotulinumtoxinB will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Ask a doctor if it is safe to breastfeed while using this medicine.
Side Effects
What are the side effects of Rimabotulinumtoxinb (Myobloc)(Intramuscular)?
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
The botulinum toxin contained in rimabotulinumtoxinB can spread to other body areas beyond where it was injected. This has caused side effects in some people after receiving botulinum toxin injections, even for cosmetic purposes. Swallowing and breathing problems can be serious life-threatening, especially in children with certain muscle problems.
Call your doctor at once if you have any of these side effects (up to several hours or weeks after an injection):
- unusual or severe muscle weakness (especially in a body area that was not injected with the medication);
- trouble breathing, talking, or swallowing;
- hoarse voice, droopy eyelids, blurred vision, double vision, or other vision problems; or
- loss of bladder control.
Common side effects may include:
- pain or discomfort where the medicine was injected;
- headache;
- dry mouth; or
- trouble swallowing.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I take Rimabotulinumtoxinb (Myobloc)(Intramuscular) if I’m pregnant or breastfeeding?
It is not known if rimabotulinumtoxinB will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Ask a doctor if it is safe to breastfeed while using this medicine.
Interactions
What drugs and food should I avoid while taking Rimabotulinumtoxinb (Myobloc)(Intramuscular)?
RimabotulinumtoxinB may impair your reactions and may cause weakness, loss of strength, or vision changes. Avoid driving or hazardous activity until you know how this medicine will affect you.
Dosage Guidelines & Tips
How to take Rimabotulinumtoxinb (Myobloc)(Intramuscular)?
Use Rimabotulinumtoxinb (Myobloc)(Intramuscular) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
RimabotulinumtoxinB is injected into a muscle or into a gland by a healthcare provider. Your doctor will determine when to receive the next dose.
Your injections may be given into more than one area at a time, depending on the condition being treated.
Your doctor may occasionally change your dose until your doctor determines the best dose.
Your doctor may need to check your progress on a regular basis, and your next dose may change based on your response to treatment.
Call your doctor if your symptoms do not improve, or if they get worse.
Do not receive botulinum toxin injections from more than one medical professional at a time. If you switch healthcare providers, be sure to tell your new provider how long it has been since your last botulinum toxin injection.
Using this medicine more often than prescribed will not make it more effective and may result in serious side effects.
Call your doctor for instructions if you miss an appointment for your rimabotulinumtoxinB injection.
Overdose Signs
What happens if I overdose on Rimabotulinumtoxinb (Myobloc)(Intramuscular)?
Overdose symptoms may not appear right away, but can include muscle weakness, trouble swallowing, weak or shallow breathing, or loss of movement in any part of your body.