Proglycem (Oral)
Diazoxide oral suspension is used in adults and children to treat low blood sugar (hypoglycemia) caused by conditions where the body makes too much insulin.
Diazoxide extended-release tablet is used to help control extreme hunger and constant food cravings (hyperphagia) in adults and children at least 4 years old with Prader-Willi syndrome (PWS).
Diazoxide may also be used for purposes not listed in this medication guide.
warnings
What is the most important information I should know about Proglycem (Oral)?
You should not use this medicine if you are allergic to diazoxide or to certain diuretics such as hydrochlorothiazide, chlorthalidone, and others.
You should not take diazoxide to treat occasional low blood sugar caused by diet.
Tell your doctor if you have or have ever had:
- heart problems;
- diabetes or prediabetes;
- gout;
- swelling in your legs and other parts of the body;
- if you have a planned surgery;
- if you are sick or dehydrated;
- if you drink large amounts of alcohol; or
- liver or kidney disease.
Using diazoxide may increase the risk of developing pulmonary hypertension in newborns and infants. Ask your doctor about this risk.
It is not known if diazoxide will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Ask a doctor if it is safe to breastfeed while using this medicine.
Side Effects
What are the side effects of Proglycem (Oral)?
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- blurred vision, eye pain or redness, seeing halos around lights;
- nausea, vomiting, stomach pain, weakness, trouble breathing;
- fluid build-up in or around the lungs--feeling short of breath while lying down, wheezing, gasping for breath, cough with foamy mucus, cold and clammy skin, anxiety, rapid heartbeats;
- fluid retention--shortness of breath (even while lying down), swelling, rapid weight gain (especially in your face and midsection); or
- high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor.
Your treatment may change, be delayed, or be permanently discontinued if you have certain side effects.
Common side effects may include:
- severely high blood sugar;
- pounding heartbeats or fluttering in your chest;
- swelling in your hands or feet, puffiness in your face;
- increased body hair growth;
- abnormal blood tests;
- rash, headache, weakness, feeling unwell;
- nausea, vomiting, stomach pain, loss of appetite, diarrhea;
- high sugar in your urine and blood; or
- decreased sense of taste.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I take Proglycem (Oral) if I’m pregnant or breastfeeding?
It is not known if diazoxide will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Ask a doctor if it is safe to breastfeed while using this medicine.
Interactions
What drugs and food should I avoid while taking Proglycem (Oral)?
Drinking alcohol may increase certain side effects of diazoxide.
Dosage Guidelines & Tips
How to take Proglycem (Oral)?
Use Proglycem (Oral) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Your dose needs may change if you switch to a different brand, strength, or form of this medicine. Avoid medication errors by using exactly as directed on the label, or as prescribed by your doctor.
Diazoxide oral suspension is usually taken every 8 to 12 hours. Take the medicine at the same time intervals each day.
Diazoxide extended-release tablets are usually taken once per day with or without food, at the same time each day.
Shake the oral suspension (liquid). Measure a dose with the supplied measuring device (not a kitchen spoon).
Swallow the extended-release tablet whole and do not crush, chew, or break it.
Doses are based on weight. Your dose may change if you gain or lose weight.
Do not change your dose or stop using a medicine without your doctor's advice.
Your blood sugar will need to be checked on a regular basis, and you may need other medical tests. Your treatment may change or be delayed based on the results.
This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using diazoxide.
Diazoxide is only part of a treatment program that may also include diet. Follow your doctor's instructions very closely.
Store at room temperature away from moisture and heat. Store the oral suspension in the original carton, protect from light.
Keep the extended-release tablet bottle tightly closed when not in use.
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.