Proamatine (Oral)
Midodrine is used to treat low blood pressure (hypotension) that causes severe dizziness or a light-headed feeling, like you might pass out. This medicine is for use only when low blood pressure affects daily life. Midodrine may not improve your ability to perform daily activities
Midodrine may also be used for purposes not listed in this medication guide.
uses
What is Proamatine (Oral) used for?
- Hypotension
- Hypotension Secondary to Hemodialysis
warnings
What is the most important information I should know about Proamatine (Oral)?
You should not use midodrine if you are allergic to it, or if you have:
- severe heart disease;
- if you are unable to urinate;
- pheochromocytoma (tumor of the adrenal gland);
- overactive thyroid;
- high blood pressure (even while lying down); or
- kidney disease.
To make sure midodrine is safe for you, tell your doctor if you have or have ever had:
- diabetes;
- glaucoma or a history of vision problems; or
- liver disease.
It is not known if midodrine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Ask a doctor if it is safe to breastfeed while using this medicine.
Side Effects
What are the side effects of Proamatine (Oral)?
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- severely slowed heart rate--weak pulse, severe dizziness or light-headed feeling; or
- dangerously high blood pressure--severe headache, pounding sensation in your ears ("hearing" your heartbeats), blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure.
Common side effects may include:
- increased blood pressure when sitting or lying down;
- chills, goosebumps;
- numbness, tingling, or itching (especially in your scalp); or
- increased urination, painful or difficult urination, or sudden urge to urinate.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I take Proamatine (Oral) if I’m pregnant or breastfeeding?
It is not known if midodrine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Ask a doctor if it is safe to breastfeed while using this medicine.
Interactions
What drugs and food should I avoid while taking Proamatine (Oral)?
Avoid taking a dose if it is less than 4 hours before going to bed.
Ask a doctor or pharmacist before using any over-the-counter diet or cough/cold medicine containing phenylephrine or pseudoephedrine. These medicines may raise your blood pressure.
Dosage Guidelines & Tips
How to take Proamatine (Oral)?
Use Proamatine (Oral) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Midodrine is usually taken 3 times per day, with doses spaced at least 3 hours apart. Take your last dose of the day before evening meal or 4 hours before bedtime.
You may take midodrine with or without food.
Take this medicine during your normal waking hours, when your are most likely to be upright and not lying down or napping. Ask your doctor about how to take this medicine if you normally lie down during the day.
Midodrine can increase your blood pressure even while you are lying down or sleeping (when blood pressure is usually lowest). Long-term high blood pressure (hypertension) can lead to serious medical problems.
Follow your doctor's instructions about the best way to position your body while you are laying down or sleeping. You may need to keep your head elevated to help prevent high blood pressure.
Your blood pressure will need to be checked before and during treatment with midodrine. Check your blood pressure while you are lying down, and check it again with your head elevated.
Your kidney and liver function may also need to be checked.
Midodrine is only part of a treatment program that may also include lifestyle changes, wearing support stockings on your legs, and possibly special medical care. Follow your doctor's instructions very carefully.
Store at room temperature away from moisture and heat.
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
You may need to skip a dose if you will be resting or lying down for a long period of time during your normal waking hours. Talk to your doctor about how to adjust your dose schedule if needed.
Overdose Signs
What happens if I overdose on Proamatine (Oral)?
Overdose symptoms include increased blood pressure (flushing, headache, pounding heartbeat, blurred vision), goosebumps, feeling cold, or trouble urinating.
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