Miglustat (Zavesca)
Miglustat is used to treat mild to moderate type 1 Gaucher disease in adults who cannot receive enzyme replacement therapy.
Miglustat may also be used for purposes not listed in this medication guide.
uses
What is Miglustat (Zavesca) used for?
- Gaucher Disease
warnings
What is the most important information I should know about Miglustat (Zavesca)?
Tell your doctor if you have or have ever had:
- inflammatory bowel disease;
- nervous system problems;
- a condition that causes tremors or shaking; or
- kidney disease.
Miglustat may harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Do not breastfeed while using this medicine.
Side Effects
What are the side effects of Miglustat (Zavesca)?
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- tremor or uncontrolled shaking, especially in your hands;
- numbness, tingling, or burning pain in your hands or feet;
- severe diarrhea and weight loss; or
- low levels of platelets in your blood--easy bruising or bleeding (nosebleeds, bleeding gums).
Common side effects may include:
- gas, bloating, constipation;
- nausea, vomiting, loss of appetite, weight loss, stomach pain or upset;
- dry mouth;
- dizziness, weakness;
- headache (including migraine);
- back pain, muscle cramps, leg cramps;
- heavy feeling in your arms or legs;
- memory problems, loss of balance or coordination;
- numbness, tingling, or burning pain in your skin;
- vision problems; or
- changes in your menstrual periods.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I take Miglustat (Zavesca) if I’m pregnant or breastfeeding?
Miglustat may harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Do not breastfeed while using this medicine.
Interactions
What drugs and food should I avoid while taking Miglustat (Zavesca)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Dosage Guidelines & Tips
How to take Miglustat (Zavesca)?
Use Miglustat (Zavesca) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Miglustat is usually taken 3 times per day at the same time each day.
You may be given other medications to help treat certain side effects. Keep taking these medicines for as long as your doctor has prescribed.
You may need to follow a special diet that avoids foods high in carbohydrates. Follow all instructions of your doctor or dietitian. Learn about the foods you should eat or avoid.
You may need medical tests to check your nerve function before and during treatment with miglustat.
Your blood may also need to be tested while you are using miglustat.
Store at room temperature away from moisture and heat.
Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.
Overdose Signs
What happens if I overdose on Miglustat (Zavesca)?
Images
310, AMG
Color: white
Shape: capsule
Imprint: 310, AMG
709
Color: white
Shape: capsule
Imprint: 709
OGT 918, 100
Color: white
Shape: capsule
Imprint: OGT 918, 100