Marstacimab (Subcutaneous)
Marstacimab is used in adults and children at least 12 years old with hemophilia A or B (without inhibitors) to help prevent bleeding episodes or make them occur less often.
Your doctor will make sure you can be treated with marstacimab.
Marstacimab may also be used for purposes not listed in this medication guide.
uses
What is Marstacimab (Subcutaneous) used for?
- Bleeding
- Retinal Hemorrhage
- Threatened Abortion
- Gastrointestinal Hemorrhage
- Thrombotic Thrombocytopenic Purpura
- Mallory-Weiss Syndrome
- Hemorrhagic Nephrosonephritis
- Duodenitis/Gastritis with Hemorrhage
- Alcoholic Gastritis with Hemorrhage
- Peptic Ulcer with Hemorrhage
- Peptic Ulcer with Hemorrhage and Perforation
- Peptic Ulcer with Hemorrhage and Obstruction
- Peptic Ulcer with Hemorrhage/Perforation/Obstruction
- Diverticulitis with Hemorrhage
- Intracranial Hemorrhage
- Syphilitic Ruptured Cerebral Aneurysm
- Head Injury with Intracranial Hemorrhage
- Head Injury w/ Intracranial Hemorrhage and Loss of Consciousness
- Esophageal Varices with Bleeding
- Esophageal Hemorrhage
- Bleeding Associated with Coagulation Defect
- Adrenal Hemorrhage
- Pulmonary Hemorrhage
- Hemorrhagic Fever
- Hemopericardium
- Thyroid Hemorrhage/Infarction
- Waterhouse-Friderichsen Syndrome
- Goodpasture's Syndrome
- Allergic Purpura
- Gastrointestinal Diverticula with Hemorrhage
- Esophageal Ulceration with Bleeding
warnings
What is the most important information I should know about Marstacimab (Subcutaneous)?
Tell your doctor if you also use factor or non-factor based medicines. Your healthcare provider will provide instructions for stopping your current treatment when switching to marstacimab.
Tell your doctor if you have or have ever had:
- a planned surgery;
- serious infection, sepsis (a severe reaction to an infection); or
- recent injury or trauma.
May harm an unborn baby. You may need a pregnancy test to make sure you are not pregnant. Use effective birth control while using marstacimab and for at least 2 months after your last dose. Tell your doctor if you become pregnant.
Ask a doctor if it is safe to breastfeed while using this medicine.
Side Effects
What are the side effects of Marstacimab (Subcutaneous)?
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- fast or pounding heartbeats;
- chest or back pain, feeling short of breath, coughing up blood;
- swelling, pain, redness, or skin discoloration in your arms or legs;
- headache, dizziness, fainting, sweating;
- numbness in your face; or
- eye pain or swelling, vision problems.
Common side effects may include:
- pain, bruising, swelling, redness, itching, irritation or hardening where the medicine was injected.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I take Marstacimab (Subcutaneous) if I’m pregnant or breastfeeding?
May harm an unborn baby. You may need a pregnancy test to make sure you are not pregnant. Use effective birth control while using marstacimab and for at least 2 months after your last dose. Tell your doctor if you become pregnant.
Ask a doctor if it is safe to breastfeed while using this medicine.
Interactions
What drugs and food should I avoid while taking Marstacimab (Subcutaneous)?
Do not inject into areas where the skin is tender, bruised, red, or hard. Avoid injecting into skin that has scars or stretch marks.
Dosage Guidelines & Tips
How to take Marstacimab (Subcutaneous)?
Use Marstacimab (Subcutaneous) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Marstacimab is injected under the skin, usually once every week.
Your healthcare provider will show you where to inject marstacimab. Do not inject into the same place two times in a row.
Prepare an injection only when you are ready to give it. Call your pharmacist if the medicine looks cloudy, has changed colors or has particles in it.
Throw away a prefilled syringe after one use, even if there is still medicine left inside.
If you need surgery, tell the surgeon ahead of time that you are using marstacimab. You will need to stop using the medicine for a short time.
Do not use marstacimab to treat breakthrough bleeding. You may be given other medicines to treat breakthrough bleeding during treatment with marstacimab. Follow your doctor's instructions very carefully.
Call your doctor if your symptoms do not improve, or if they get worse.
Store this medicine in the original container in the refrigerator. Protect from light and do not freeze or shake the medicine.
Do not warm the medicine with hot water, sunlight, or a microwave.
Take the medicine out of the refrigerator and let it reach room temperature before using.
You may store this medicine at room temperature for up to 7 days. Throw the medicine away if not used within 7 days. Do not put it back into the refrigerator.
Use the medicine as soon as you remember, and then go back to your regular schedule. Do not use two doses at one time.