Hydromorphone (Injection) - Side Effects, Interactions, Uses, Dosage, Warnings

Hydromorphone (Injection)(Injectable,Intravenous)

Hydromorphone (Injection)(Injectable,Intravenous)

Hydromorphone injection is an opioid medicine used to treat severe pain.

Hydromorphone injection may also be used for purposes not listed in this medication guide.

uses

What is Hydromorphone (Injection)(Injectable,Intravenous) used for?

warnings

What is the most important information I should know about Hydromorphone (Injection)(Injectable,Intravenous)?

You should not use hydromorphone if you have ever had an allergic reaction to a narcotic medicine, or if you have:

  • severe asthma or breathing problems; or
  • a bowel obstruction called paralytic ileus.

Do not use hydromorphone if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine. Wait at least 14 days after stopping an MAO inhibitor before you take hydromorphone.

Tell your doctor if you have ever had:

  • breathing problems, sleep apnea;
  • a head injury, brain tumor, or seizures;
  • low blood pressure;
  • alcoholism, drug addiction, mental illness;
  • urination problems;
  • a sulfite allergy;
  • a pancreas disorder;
  • Addison's disease or other adrenal gland disorders; or
  • liver or kidney disease.

May harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. If you use hydromorphone for an extended period of time during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor if it is safe to breastfeed while using this medicine. Hydromorphone in breast milk can cause life-threatening side effects in a nursing baby.

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Side Effects

What are the side effects of Hydromorphone (Injection)(Injectable,Intravenous)?

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Opioid medicine can slow or stop your breathing, and death may occur. A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.

Call your doctor at once if you have:

  • breathing that stops during sleep;
  • slow heart rate, weak pulse, fainting, slow breathing (breathing may stop);
  • confusion, feelings of extreme happiness or sadness;
  • severe weakness or drowsiness;
  • worsening pain, more sensitivity towards pain;
  • a light-headed feeling, like you might pass out; or
  • low cortisol levels--nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness.

Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Serious side effects may be more likely in older adults and those who are malnourished or debilitated.

Common side effects may include:

  • constipation, nausea, vomiting;
  • dizziness, drowsiness;
  • flushing (warmth, redness, or tingly feeling);
  • sweating, itching;
  • dry mouth; or
  • mood changes.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Hydromorphone (Injection)(Injectable,Intravenous) if I’m pregnant or breastfeeding?

May harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. If you use hydromorphone for an extended period of time during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor if it is safe to breastfeed while using this medicine. Hydromorphone in breast milk can cause life-threatening side effects in a nursing baby.

Interactions

What drugs and food should I avoid while taking Hydromorphone (Injection)(Injectable,Intravenous)?

Do not drink alcohol. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

Dosage Guidelines & Tips

How to take Hydromorphone (Injection)(Injectable,Intravenous)?

Use Hydromorphone (Injection)(Injectable,Intravenous) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Hydromorphone is injected into a muscle, under the skin, or into a vein.

Hydromorphone is usually given by injection only if you are unable to take medicine by mouth.

Never share opioid medicine with another person, especially someone with a history of drug addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine where others cannot get to it. Selling or giving away this medicine is against the law.

Do not stop using hydromorphone suddenly, or you could have unpleasant symptoms (such as agitation, confusion, tingling or electric shock feelings). Ask your doctor before stopping the medicine.

In a medical setting you are not likely to miss a dose.

Overdose Signs

What happens if I overdose on Hydromorphone (Injection)(Injectable,Intravenous)?

In a medical setting an overdose would be treated quickly.

If you think you or someone else may have overdosed on: Hydromorphone (Injection)(Injectable,Intravenous),  call your doctor or the Poison Control center
(800) 222-1222
If someone collapses or isn't breathing after taking Hydromorphone (Injection)(Injectable,Intravenous), call 911
911

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Medical Disclaimer

Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. Cerner Multum™ provides the data within some of the Overview, Uses, Warnings, Side Effects, Pregnancy, Interactions, Dosage, Overdose, and Images sections. The information within all other sections is proprietary to Everyday Health.