Gadoxetate (Intravenous)
Gadoxetate is a contrast agent that has magnetic properties. It is used in combination with magnetic resonance imaging (MRI) to allow blood vessels, organs, and other non-bony tissues to be seen more clearly.
Gadoxetate is used to help diagnose certain disorders of the liver.
Gadoxetate may also be used for purposes not listed in this medication guide.
uses
What is Gadoxetate (Intravenous) used for?
- Liver Magnetic Resonance Imaging
warnings
What is the most important information I should know about Gadoxetate (Intravenous)?
Gadoxetate can cause a life-threatening condition in people with advanced kidney disease. Ask your doctor about your individual risk.
Gadoxetate can stay in your body for months or years after you receive this medicine. It is not known whether this could cause any health problems in people whose kidneys work properly. Tell your doctor if you have had repeated scans with a contrast agent, and provide the date of your last scan.
You should not receive gadoxetate if you are allergic to it.
Tell your doctor if you have ever had:
- any type of reaction to a contrast agent;
- diabetes;
- high blood pressure;
- asthma, hay fever, food or drug allergies; or
- liver or kidney disease.
It is not known if gadoxetate will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Tell your doctor if you are breastfeeding. Do not breastfeed within 10 hours after using gadoxetate. If you use a breast pump during this time, throw out the milk and do not feed it to your baby.
Side Effects
What are the side effects of Gadoxetate (Intravenous)?
Get emergency medical help if you have signs of an allergic reaction: hives, difficulty breathing, swelling of your face, lips, tongue, or throat.
Some side effects of gadoxetate may occur up to several days after injection.
Gadoxetate can cause a life-threatening condition in people with advanced kidney disease. Call your doctor right away if you have any symptoms of this condition, such as:
- burning, itching, swelling, scaling, and tightening or hardening of your skin;
- skin redness or dark patches;
- muscle weakness;
- joint stiffness in your arms, hands, legs, or feet;
- pain; or
- tiredness, trouble moving.
Call your doctor at once if you have:
- kidney problems--little or no urinating, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath;
- a seizure (convulsions); or
- swelling, irritation, or skin changes where the injection was given.
Common side effects may include:
- headache, back pain;
- dizziness;
- altered sense of taste, nausea; or
- feeling hot.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I take Gadoxetate (Intravenous) if I’m pregnant or breastfeeding?
It is not known if gadoxetate will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Tell your doctor if you are breastfeeding. Do not breastfeed within 10 hours after using gadoxetate. If you use a breast pump during this time, throw out the milk and do not feed it to your baby.
Interactions
What drugs and food should I avoid while taking Gadoxetate (Intravenous)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Dosage Guidelines & Tips
How to take Gadoxetate (Intravenous)?
Use Gadoxetate (Intravenous) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Gadoxetate is given as an infusion into a vein. A healthcare provider will give you this injection.
You will be watched for a short time to make sure you do not have an allergic reaction.
Gadoxetate can affect the results of certain medical tests. Tell any doctor who treats you that you are using gadoxetate
In a medical setting you are not likely to miss a dose.
Overdose Signs
What happens if I overdose on Gadoxetate (Intravenous)?
In a medical setting an overdose would be treated quickly.