Dasiglucagon (Zegalogue)
Dasiglucagon is used in adults and children at least 6 years and older with diabetes to treat very low blood sugar (severe hypoglycemia).
Dasiglucagon may also be used for purposes not listed in this medication guide.
warnings
What is the most important information I should know about Dasiglucagon (Zegalogue)?
You should not use dasiglucagon if you have or have ever had:
- a tumor of the pancreas (insulinoma); or
- pheochromocytoma (tumor of the adrenal gland).
Tell your doctor if you have or have ever had:
- any tumor of the pancreas;
- an allergy to this medicine or any of its ingredients;
- chronic low blood sugar;
- adrenal gland problems;
- an allergy to latex; or
- if you have not had food or water regularly for a long period.
It is not known if dasiglucagon will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Ask a doctor if it is safe to breastfeed while using this medicine.
In an emergency situation, it may not be possible to tell your caregivers if you are pregnant or breast-feeding. Make sure any doctor caring for your pregnancy or your baby knows you have received this medicine.
Side Effects
What are the side effects of Dasiglucagon (Zegalogue)?
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- severe headache, blurred vision, pounding in your neck or ears; or
- low blood sugar--hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery.
Common side effects may include:
- nausea, vomiting, diarrhea;
- headache; or
- pain where an injection was given.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I take Dasiglucagon (Zegalogue) if I’m pregnant or breastfeeding?
It is not known if dasiglucagon will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Ask a doctor if it is safe to breastfeed while using this medicine.
In an emergency situation, it may not be possible to tell your caregivers if you are pregnant or breast-feeding. Make sure any doctor caring for your pregnancy or your baby knows you have received this medicine.
Interactions
What drugs and food should I avoid while taking Dasiglucagon (Zegalogue)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Dosage Guidelines & Tips
How to take Dasiglucagon (Zegalogue)?
Use Dasiglucagon (Zegalogue) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Hypoglycemia should be treated as quickly as possible. Having low blood sugar for too long can cause seizure, coma, or death.
Dasiglucagon is injected under the skin. A healthcare provider will teach you or your caregiver how to properly use this medicine. Call your doctor after each time you use a dasiglucagon injection.
Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don't understand how to use an injection.
Prepare an injection only when you are ready to give it. Call your pharmacist if the medicine looks cloudy, has changed colors or has particles in it.
Do not inject within 2 inches of your navel (belly button). Your healthcare provider will show where to inject dasiglucagon injection.
After the injection, you should eat a fast-acting source of sugar (fruit juice, glucose gel, hard candy, raisins, or non-diet soda) and then eat a snack or small meal such as cheese or peanut butter and crackers.
If you are a caregiver, get emergency medical help after giving a dasiglucagon injection. If the patient does not improve within 15 minutes, you may need to give a second injection.
Throw away a prefilled syringe or autoinjector after one use, even if there is still medicine left inside. Do not reuse a needle, syringe, or autoinjector. Place them in a puncture-proof "sharps" container and dispose of it following state or local laws. Keep out of the reach of children and pets.
Blood sugar can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.
To keep from having severe hypoglycemia, follow your diet, medication, and exercise routines very closely.
Store in the refrigerator, away from the cooling element. Do not freeze.
You may store this medicine at room temperature for up to 12 months. Protect from light by storing the medicine in the protective case. Throw the medicine away if not used within 12 months. Do not return the medicine into the refrigerator once it has reached room temperature.
Dasiglucagon is used when needed. If you are on a dosing schedule, skip any missed dose. Do not use two doses at one time.