Question 1

What is Cytoxan (Intravenous,Oral) used for?

Accepted Answer

Nephrotic Syndrome
Malignant Disease

Question 2

What is the most important information I should know about Cytoxan (Intravenous,Oral)?

Accepted Answer

You should not use this medicine if you are allergic to cyclophosphamide or similar medicines, or if you have:

a bladder obstruction.

Tell your doctor if you have or have ever had:

weak immune system (caused by disease or by using certain medicines);
an active or chronic infection (including a bladder infection);
drink alcohol;
bladder problems;
lung disease;
heart disease;
if you are receiving other cancer treatments or radiation;
kidney disease (or if you are on dialysis); or
liver disease.

Using cyclophosphamide may increase your risk of developing other cancers. Ask your doctor about this risk. You may need to have a negative pregnancy test before starting this treatment. May harm an unborn baby. Do not use if you are pregnant. Use effective birth control while using cyclophosphamide and for at least 1 year after your last dose. Tell your doctor if you become pregnant. Men using cyclophosphamide should use condoms during treatment, and for at least 4 months after treatment ends. Cyclophosphamide may affect fertility in men or women. Pregnancy could be harder to achieve while either parent is using this medicine. Cyclophosphamide may cause you to stop having menstrual periods. Your periods should return to normal within a few months after you stop using cyclophosphamide. However, older women may have early menopause due to this effect. Talk to your doctor about this risk. Do not breastfeed while using this medicine, and for at least 1 week after your last dose.

Question 3

Can I take Cytoxan (Intravenous,Oral) if I’m pregnant or breastfeeding?

Accepted Answer

You may need to have a negative pregnancy test before starting this treatment. May harm an unborn baby. Do not use if you are pregnant. Use effective birth control while using cyclophosphamide and for at least 1 year after your last dose. Tell your doctor if you become pregnant. Cyclophosphamide may cause you to stop having menstrual periods. Your periods should return to normal within a few months after you stop using cyclophosphamide. However, older women may have early menopause due to this effect. Talk to your doctor about this risk. Do not breastfeed while using this medicine, and for at least 1 week after your last dose.

Question 4

How to take Cytoxan (Intravenous,Oral)?

Accepted Answer

Use Cytoxan (Intravenous,Oral) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Cyclophosphamide oral is taken by mouth. Doses are based on weight. Your dose may change if you gain or lose weight. Swallow the tablet/capsule whole and do not crush, chew, or break it. Cyclophosphamide injection is given as an infusion into a vein. A healthcare provider will give you this injection. Cyclophosphamide should be taken in the morning. Drink plenty of liquids while you are using cyclophosphamide. Cyclophosphamide affects your immune system. You may get infections more easily, even serious or fatal infections. Your doctor will need to examine you on a regular basis. Cyclophosphamide can lower your blood cell counts. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results. If you need surgery, tell the surgeon ahead of time that you are using cyclophosphamide. You may need to stop using the medicine for a short time. Ask your doctor or pharmacist how to safely handle this medicine. Cyclophosphamide can be harmful if it gets on your skin. If this occurs, wash thoroughly with soap and water. Your caregiver may need to wear latex gloves when handling this medicine. Store at room temperature away from moisture and heat.

Question 5

What happens if I overdose on Cytoxan (Intravenous,Oral)?

Accepted Answer

If you think you or someone else may have overdosed Cytoxan (Intravenous,Oral) call your doctor or the Poison Control center '800-222-1222','(800) 222-1222','Poison Control' If someone collapses or isn't breathing after taking Diclofenac (Voltaren), call 911

Question 6

What drugs and food should I avoid while taking Cytoxan (Intravenous,Oral)?

Accepted Answer

This medicine may cause blurred vision and may impair your reactions. Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries. Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.

Question 7

What are the side effects of Cytoxan (Intravenous,Oral)?

Accepted Answer

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat. This medicine can cause serious or fatal side effects, including:

unusual bruising or bleeding, new signs of infection (fever, weakness, cough, diarrhea, burning when you urinate);
bone marrow suppression;
feeling short of breath on exertion;
chest discomfort, dry cough or hack;
feeling weak or tired, loss of appetite, rapid weight loss;
kidney problems--swelling, urinating less, feeling tired or short of breath, blood in urine;
heart problems--swelling, rapid weight gain, feeling short of breath;
liver problems--loss of appetite, nausea, vomiting, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
low blood sodium--headache, confusion, problems with thinking or memory, weakness, feeling unsteady; or
low blood cell counts--fever, chills, tiredness, blisters or ulcers in your mouth, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath.

Common side effects may include:

fever, low blood cell counts;
mouth sores;
nausea, vomiting, diarrhea;
hair loss; or
missed menstrual periods.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.