Conjugated Estrogens (Oral)(Oral)
Conjugated estrogens is used in menopause adult women to treat certain symptoms of menopause such as hot flashes and vaginal dryness, burning, and irritation.
Conjugated estrogens is also used in menopause adult women to prevent osteoporosis (bone loss).
Conjugated estrogens may also be used before menopause in women to treat lack of estrogen that is caused by certain conditions such as hypogonadism, ovarian failure, or surgical removal.
Conjugated estrogens is sometimes used in both women and men to reduce symptoms of certain cancers that have spread to other parts of the body.
Conjugated estrogens may also be used for purposes not listed in this medication guide.
uses
What is Conjugated Estrogens (Oral)(Oral) used for?
- Abnormal Uterine Bleeding
- Atrophic Vaginitis
- Hypoestrogenism
- Osteoporosis
- Postmenopausal Symptoms
- Primary Ovarian Failure
- Prostate Cancer
- Breast Cancer--Palliative
warnings
What is the most important information I should know about Conjugated Estrogens (Oral)(Oral)?
You should not use conjugated estrogens if you are allergic to it or any of its ingredients, or if you have or have ever had:
Conjugated estrogens should not be used to prevent heart disease, stroke, or dementia. especially if you have high blood pressure, diabetes, high cholesterol, if you are overweight, or if you smoke. Using this medicine may increase your risk of blood clots, dementia, stroke, or heart attack,
Do not use conjugated estrogens if you are pregnant. Tell your doctor right away if you become pregnant or think you may be pregnant.
Ask a doctor if it is safe to breastfeed while using this medicine.
- unusual vaginal bleeding that has not been checked by a doctor;
- a heart attack, stroke, or blood clot;
- a bleeding or blood clotting disorder;
- hormone related cancer such as breast or uterine cancer; or
- liver disease.
- heart disease;
- gallbladder disease;
- asthma;
- epilepsy or other seizure disorder;
- migraines;
- bone cancer;
- a family history of breast cancer;
- systemic lupus erythematosus (SLE);
- diabetes;
- endometriosis or uterine fibroid tumors;
- hereditary angioedema;
- porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system);
- high triglycerides;
- a thyroid disorder;
- hypoparathyroidism;
- abnormal levels of calcium in your blood;
- endometrial hyperplasia (overgrowth of cells lining the uterus);
- if you have had your uterus removed (hysterectomy);
- liver problems such as a liver tumor or jaundice (caused by pregnancy or hormones); or
- kidney disease.
Tell your doctor if you have or have ever had:
Long-term use of conjugated estrogens may increase your risk of cancer of the breast or uterus. Talk with your doctor about this risk.
Side Effects
What are the side effects of Conjugated Estrogens (Oral)(Oral)?
Get emergency medical help if you have : hives, difficult breathing, swelling of your face, lips, tongue, or throat. signs of an allergic reaction
Call your doctor at once if you have:
Conjugated estrogens can increase your risk of blood clots, stroke, or heart attack. Get emergency medical help if you have: chest pain, pain, swelling or warmth in your leg, sudden numbness or weakness on one side of the body, slurred speech, feeling short of breath or trouble breathing.
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
- change in the pattern or severity of migraine headaches;
- memory problems, confusion, unusual behavior;
- unusual vaginal bleeding;
- a lump in your breast;
- changes in vision;
- abnormal lab results such as increased fat in your blood (triglycerides) or thyroid hormone levels;
- signs of gallbladder, liver, or pancreas problems--chalky-colored stools, stomach pain after eating, nausea, heartburn, bloating, loss of appetite, upper stomach pain (that may spread to your back), vomiting, fast heart rate, dark urine, jaundice (yellowing of the skin or eyes);
- fluid retention--shortness of breath (even while lying down), swelling, rapid weight gain (especially in your face and midsection);
- increased blood pressure--severe headache, pounding in your neck or ears; or
- low or high blood calcium levels--constipation, increased thirst or urination, muscle spasms, weight loss, tingly feeling (around your mouth, or in your fingers and toes).
- sleep problems (insomnia);
- weakness or lack of energy;
- depression;
- hair loss;
- nausea, vomiting, stomach pain or cramps;
- bloating, swelling, weight gain;
- headache;
- breast pain and tenderness; or
- vaginal itching or discharge, irregular vaginal bleeding or spotting.
Pregnancy & Breastfeeding
Can I take Conjugated Estrogens (Oral)(Oral) if I’m pregnant or breastfeeding?
Do not use conjugated estrogens if you are pregnant. Tell your doctor right away if you become pregnant or think you may be pregnant.
Ask a doctor if it is safe to breastfeed while using this medicine.
Interactions
What drugs and food should I avoid while taking Conjugated Estrogens (Oral)(Oral)?
Avoid smoking. It can greatly increase your risk of blood clots, dementia, stroke, or heart attack while using this medicine.
Grapefruit may interact with conjugated estrogens and cause side effects. Avoid consuming grapefruit products.
Dosage Guidelines & Tips
How to take Conjugated Estrogens (Oral)(Oral)?
Use Conjugated Estrogens (Oral)(Oral) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Conjugated estrogens may be taken daily or in cycles (such as 3 weeks on followed by 1 week off) depending on your medical condition. Follow your doctor's instructions.
You may take conjugated estrogens with or without food.
If you see part of a tablet in your stool, talk with your doctor.
If you are taking this medicine to prevent osteoporosis, your doctor may recommend weight-bearing exercises like walking or running, plus calcium and vitamin D supplements.
If you need surgery, or will be on bed rest, tell your healthcare provider ahead of time that you are using conjugated estrogens. You may need to stop using the medicine for a short time.
You may need frequent medical tests and your doctor will need to check your progress on a regular basis to determine how long you should use conjugated estrogens. You may need a pelvic exam, breast exam, and mammogram every year while using conjugated estrogens. Follow your doctor's instructions.
This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using conjugated estrogens.
Conjugated estrogens may increase your risk of developing a condition that can lead to uterine cancer. To lower this risk, your doctor may also want you to take a progestin. Report any unusual vaginal bleeding right away.
Store at room temperature away from moisture and heat.
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. take two doses at one time. Do not
Overdose Signs
What happens if I overdose on Conjugated Estrogens (Oral)(Oral)?
Images
PREMARIN 0.3
Color: green
Shape: oval
Imprint: PREMARIN 0.3
PREMARIN 0.45
Color: blue
Shape: oval
Imprint: PREMARIN 0.45
Premarin 0.625
Color: maroon
Shape: oval
Imprint: Premarin 0.625