Anzupgo (Topical)
Delgocitinib topical (for the skin) is used in adults to treat moderate to severe chronic eczema (atopic dermatitis) affecting the hands.
Delgocitinib topical is given after other treatments are not recommended, did not work, or stopped working
Delgocitinib topical may also be used for purposes not listed in this medication guide.
uses
What is Anzupgo (Topical) used for?
- Dermatitis Herpetiformis
- Eczema
- Sunburn
- Dermatitis - Drug-Induced
- Diaper Rash
warnings
What is the most important information I should know about Anzupgo (Topical)?
Before you start using delgocitinib topical, tell your doctor if you have any signs of infection such as fever, chills, shortness of breath, cough, body aches, tiredness, open sores or skin wounds, diarrhea, stomach pain, weight loss, painful urination, or coughing up blood.
Tell your doctor if you have or have ever had:
- an active or chronic infection;
- tuberculosis or have been near people who have tuberculosis;
- herpes zoster (also called shingles);
- hepatitis B or C;
- any type of cancer;
- if you recently received a vaccine or are scheduled to receive a vaccine;
- high cholesterol; or
- a heart attack, stroke, blood clot, or other heart problems.
Tell your doctor if you've had or been exposed to tuberculosis, or if you recently traveled. Some infections are more common in certain parts of the world, and you may have been exposed during travel.
Make sure you are current on all vaccines before you start using delgocitinib topical.
This medicine may increase your risk of certain types of skin cancer. Your healthcare provider will check your skin on a regular basis. Report any new or changing skin lesions.
It is not known if delgocitinib topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Ask a doctor if it is safe to breastfeed while using this medicine.
If you breastfeed, avoid touching your nipple area right away after applying delgocitinib topical to your hands and wrists.
Side Effects
What are the side effects of Anzupgo (Topical)?
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
- signs of a blood clot--sudden numbness or weakness (especially on one side of the body), severe headache, slurred speech, problems with vision or balance, chest pain, sudden cough or shortness of breath, dizziness, coughing up blood, pain, swelling, or warmth in one leg;
- signs of infection--fever, chills, sore throat, body aches, unusual tiredness, loss of appetite, bruising or bleeding;
- signs of tuberculosis--fever, cough, night sweats, loss of appetite, weight loss, and feeling very tired; or
- signs of shingles or eczema herpeticum--flu-like symptoms, painful blistering rash.
Common side effects may include:
- pain, tingling, itching, or redness in the area of the skin where the medicine was applied;
- skin and nail infections; or
- low white blood cell counts.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I take Anzupgo (Topical) if I’m pregnant or breastfeeding?
It is not known if delgocitinib topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Ask a doctor if it is safe to breastfeed while using this medicine.
If you breastfeed, avoid touching your nipple area right away after applying delgocitinib topical to your hands and wrists.
Interactions
What drugs and food should I avoid while taking Anzupgo (Topical)?
Delgocitinib topical may increase your risk of of skin cancer. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
Avoid receiving a "live" vaccine right before starting, during, or right after treatment with delgocitinib topical. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster (shingles).
Avoid getting this medicine in your eyes, nose, mouth, or genitals. If contact does occur, rinse well with water.
Dosage Guidelines & Tips
How to take Anzupgo (Topical)?
Use Anzupgo (Topical) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the lowest effective dose for your condition.
Do not take by mouth. Delgocitinib topical is for use only on the skin of the hands and wrists.
Wash and dry your hands or wrists before applying this medicine. Use a mild soap to clean the skin area to be treated.
Use only a small amount of medicine. Apply a thin layer twice a day to the affected areas and rub in gently.
If a caregiver applies delgocitinib topical for you, they should wash their hands after applying this medicine.
You may get infections more easily, even serious or fatal infections.
You will need frequent medical tests before and during treatment with delgocitinib topical.
Store at room temperature away from moisture and heat. Do not freeze.
Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.